AUTOCORRELATION FUNCTIONS OF NOISY ELECTRON MICROGRAPHS OF STAINED POLYNUCLEOTIDE CHAINS

被引：11

作者：

FISKIN, AM

BEER, M

机构：

[1] Department of Structural Chemistry, University of Groningen

[2] Department of Biophysics, Johns Hopkins University, Baltimore, MD

来源：

SCIENCE | 1968年 / 159卷 / 3819期

关键词：

D O I：

10.1126/science.159.3819.1111

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Polyuridylic acid was deposited on carbon films in the presence of the thallous salt of mercury-p-dihydroquinone-O,O-diacetic acid under conditions leading to attachment of one of these molecules to each nucleotide. In electron micrographs of the stained polynucleotide chain, detail was obscured by the noise resulting from the substrate. Optically obtained autocorrelation functions of the distribution of density along the strands revealed peaks suggesting a structural regularity of 8 angstroms; this was interpreted as the internucleotide spacing.

引用

页码：1111 / &

共 10 条

[1]

BARTL P, IN PRESS

[2] ELECTRON STAINS .2. ELECTRON MICROSCOPIC STUDIES ON VISIBILITY OF STAINED DNA MOLECULES [J].