Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report

被引:5
作者
Koezuka, Satoshi [1 ]
Hata, Yoshinobu [1 ]
Sato, Fumitomo [1 ]
Otsuka, Hajime [1 ]
Makino, Takashi [1 ]
Tochigi, Naobumi [2 ]
Iyoda, Akira [1 ]
机构
[1] Toho Univ, Sch Med, Div Chest Surg, Tokyo 1438541, Japan
[2] Toho Univ, Sch Med, Dept Surg Pathol, Tokyo 1438541, Japan
关键词
malignant peripheral nerve sheath tumor; anterior mediastinum; mediastinal tumor;
D O I
10.3892/mco.2014.343
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, accounting for only 5% of all malignant soft-tissue sarcomas. This is the case report of a 28-year-old male patient with a MPNST located in the anterior mediastinum, originating from the phrenic nerve. The patient presented with an abnormal shadow on chest radiography and a 10-cm mass in the right anterior mediastinum was identified on computed tomography and magnetic resonance imaging. The patient subsequently underwent surgical resection. The tumor originated from the right phrenic nerve and was tightly adherent to the middle and lower lobes of the right lung, the pericardium and the diaphragm. The tumor was completely resected, along with partial resection of the adherent tissues. The histological diagnosis was spindle cell sarcoma and the final diagnosis was MPNST of the anterior mediastinum, based on the characteristic microscopic appearance indicating the nervous origin of the tumor and on the intraoperative findings. The patient remains free of recurrence 1 year after surgery.
引用
收藏
页码:987 / 990
页数:4
相关论文
共 14 条
[1]   Pediatric malignant peripheral nerve sheath tumor: The Italian and German soft tissue sarcoma cooperative group [J].
Carli, M ;
Ferrari, A ;
Mattke, A ;
Zanetti, I ;
Casanova, M ;
Bisogno, G ;
Cecchetto, G ;
Alaggio, R ;
De Sio, L ;
Koscielniak, E ;
Sotti, G ;
Treuner, J .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (33) :8422-8430
[2]  
DUCATMAN BS, 1984, CANCER, V54, P1049, DOI 10.1002/1097-0142(19840915)54:6<1049::AID-CNCR2820540620>3.0.CO
[3]  
2-1
[4]  
DUCATMAN BS, 1986, CANCER-AM CANCER SOC, V57, P2006, DOI 10.1002/1097-0142(19860515)57:10<2006::AID-CNCR2820571022>3.0.CO
[5]  
2-6
[6]  
INGELS GW, 1971, CANCER-AM CANCER SOC, V27, P1190, DOI 10.1002/1097-0142(197105)27:5<1190::AID-CNCR2820270526>3.0.CO
[7]  
2-7
[8]   Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: a multivariate analysis of the French Sarcoma Group Database [J].
Italiano, A. ;
Delva, F. ;
Mathoulin-Pelissier, S. ;
Le Cesne, A. ;
Bonvalot, S. ;
Terrier, P. ;
Trassard, M. ;
Michels, J. -J. ;
Blay, J. -Y. ;
Coindre, J. -M. ;
Bui, B. .
ANNALS OF ONCOLOGY, 2010, 21 (12) :2436-2441
[9]  
Nielsen G.P., 2013, WHO CLASSIFICATION T, P187
[10]   A malignant triton tumor in the anterior mediastinum requiring emergency surgery: Report of a case [J].
Otani, Y ;
Morishita, Y ;
Yoshida, I ;
Ishikawa, S ;
Otaki, A ;
Aihara, T ;
Nakajima, T .
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 1996, 26 (10) :834-836