TRANSPORT OF NEUTRAL AMINO-ACIDS ACROSS THE HUMAN RED BLOOD-CELL MEMBRANE

被引：9

作者：

ROSENBERG, R

RAFAELSEN, OJ

机构：

[1] Psychochemistry Institute, University of Copenhagen Rigshospitalet, Copenhagen

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY | 1979年 / 3卷 / 04期

关键词：

genetic markers; group and specific tryptophan transport system; neutral amino acid transport; Rafaelsen's model of affective disorders;

D O I：

10.1016/0364-7722(79)90049-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. 1. Genetic markers are important in the search for genetically transmitted entities related to clinical nosology with implications for etiology, prophylaxis and treatment. 2. 2. Refaelsen (1976) has proposed a membrane transport of affective disorders focusing on phase-independent transport deficiences. 3. 3. The transport of some neutral amino acids (L-leucine, L-phenylalanine and L-tryptophan) has been studied in the human erythrocyte at 25° C. 4. 4. A group- and a tryptophan-specific amino acid transport system have bean described. 5. 5. The relation to the model of Rafaelsen is discussed. 6. 6. It is concluded that clinical studies should be undertaken to test whether these biological characteristics consistent with a specific theory are biological-etiological markets. © 1981.

引用

页码：377 / 381

页数：5