MAVS: A New Weapon in the Fight Against Viral Infections

被引：4
作者：
Boga, Jose A. [1 ]
de Ona, Maria [1 ]
Melon, Santiago [1 ]
Alvarez-Arguelles, Marta E. [1 ]
Morilla, Ana [1 ]
Coto-Montes, Ana [2 ]
机构：
[1] Hosp Univ Cent Asturias, Serv Microbiol, Calle Celestino Villamil S-N, Oviedo 33006, Spain
[2] Univ Oviedo, Dept Morfol & Biol Celular, Oviedo, Spain
来源：
RECENT PATENTS ON ENDOCRINE METABOLIC & IMMUNE DRUG DISCOVERY | 2013年 / 7卷 / 02期
关键词：
Immunity; MAVS; mitochondria; viral infection;
D O I：
10.2174/1872214811307020004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
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收藏
页码：115 / 119
页数：5
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