MAVS: A New Weapon in the Fight Against Viral Infections

被引：4

作者：

Boga, Jose A. ^{[1
]}

de Ona, Maria ^{[1
]}

Melon, Santiago ^{[1
]}

Alvarez-Arguelles, Marta E. ^{[1
]}

Morilla, Ana ^{[1
]}

Coto-Montes, Ana ^{[2
]}

机构：

[1] Hosp Univ Cent Asturias, Serv Microbiol, Calle Celestino Villamil S-N, Oviedo 33006, Spain

[2] Univ Oviedo, Dept Morfol & Biol Celular, Oviedo, Spain

来源：

RECENT PATENTS ON ENDOCRINE METABOLIC & IMMUNE DRUG DISCOVERY | 2013年 / 7卷 / 02期

关键词：

Immunity; MAVS; mitochondria; viral infection;

D O I：

10.2174/1872214811307020004

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.

引用

页码：115 / 119

页数：5

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