Successful Management of Pregnancy in a Patient with Systemic Lupus Erythematosus-associated Pulmonary Arterial Hypertension

被引：2

作者：

Kawabe, Akio ^{[1
]}

Nakano, Kazuhisa ^{[1
]}

Aiko, Yukiyo ^{[2
]}

Aramaki, Satoshi ^{[2
]}

Onoue, Takeshi ^{[3
]}

Okura, Dan ^{[4
]}

Tanaka, Yoshiya ^{[1
]}

机构：

[1] Univ Occupat & Environm Hlth, Sch Med, Dept Internal Med 1, Kitakyushu, Fukuoka, Japan

[2] Univ Occupat & Environm Hlth, Sch Med, Dept Obstet & Gynecol, Kitakyushu, Fukuoka, Japan

[3] Univ Occupat & Environm Hlth, Sch Med, Dept Internal Med 2, Kitakyushu, Fukuoka, Japan

[4] Univ Occupat & Environm Hlth, Sch Med, Dept Anesthesiol, Kitakyushu, Fukuoka, Japan

来源：

INTERNAL MEDICINE | 2018年 / 57卷 / 11期

关键词：

systemic lupus erythematosus; pulmonary arterial hypertension; pregnancy; THERAPY; WOMEN;

D O I：

10.2169/internalmedicine.0033-17

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pregnancy in women with systemic lupus erythematosus (SLE)-associated pulmonary arterial hypertension (PAH) remains a high risk. We successfully managed a pregnancy in a patient with SLE-PAH. A 31-year-old pregnant woman with SLE-PAH had worsening PAH and SLE flare-up during pregnancy and a sudden increase in pulmonary arterial pressure after delivery. SLE-PAH was controlled by continuous intravenous epoprostenol and inhaled nitric oxide therapy combined with high-dose corticosteroids under close hemodynamic monitoring. Women with SLE-PAH should avoid pregnancy. However, in case of a similar event, we recommend our case as a good reference for improving the outcome of pregnancy with SLE-PAH.

引用

页码：1655 / 1659

页数：5

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