SYNTHESIS AND STUDY OF (2S,4S)-4-ARYLAMINO-2-CARBOXY-5-PYRROLIDONES

被引：4
作者：
KRASNOV, VP
NIZOVA, IA
SINITSYNA, TA
AVDYUKOVA, NV
机构：
[1] Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, 620219
来源：
RUSSIAN CHEMICAL BULLETIN | 1993年 / 42卷 / 12期
关键词：
GLUTAMIC ACID; ACID DISSOCIATION CONSTANTS; 4-ARYLAMINOPYROGLUTAMIC ACID;
D O I：
10.1007/BF00698883
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(2S,4S)-4-Arylamino-2-carboxy-5-pyrrolidones were prepared by hydrolysis of dimethyl (2S,4S)-4-arylamino-N-phthaloylglutamtaes. The protonation constants of the arylamino group in the synthesized compounds were determined. The pyrrolidone ring is stable in acidic or neutral solutions. The relative stability of the pyrrolidone ring in alkaline solutions was studied by IR spectroscopy.
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页码：2001 / 2004
页数：4
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