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- [21] Chemical and biological effects of substitution of the 2-position of ring-expanded ('fat') nucleosides containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system:: The role of electronic and steric factors on glycosidic bond stability and anti-HCV activity BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (14) : 4933 - 4945