BETA-ADRENORECEPTOR ANTAGONISTS IN ESSENTIAL TREMOR

被引：93

作者：

JEFFERSON, D

JENNER, P

MARSDEN, CD

机构：

[1] UNIV LONDON,INST PSYCHIAT,DEPT NEUROL,LONDON SE5 8AF,ENGLAND

[2] UNIV LONDON KINGS COLL HOSP,SCH MED,LONDON SE5 8RX,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1979年 / 42卷 / 10期

关键词：

D O I：

10.1136/jnnp.42.10.904

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three different β-adrenoreceptor antagonists-propranolol, sotalol, and atenololwere compared in a double-blind study with placebo in nine patients with essential tremor. All three drugs produced an equal reduction in standing pulse rate but atenolol was less effective in reducing tremor than propranolol and sotalol. These results suggest that the reduction in tremor produced by β-adrenoreceptor antagonists is mediated by an effect on peripheral β,-adrenoreceptors.

引用

页码：904 / 909

页数：6

共 31 条

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BARRETT AM, 1973, BRIT J PHARMACOL, V48, pP340

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