Statistical methods for detecting and adjusting for publication bias

被引:3
作者
Schwarzer, Guido [1 ]
Ruecker, Gerta [1 ]
机构
[1] Univ Klinikum Freiburg, Inst Med Biometrie & Med Informat, Freiburg, Germany
来源
ZEITSCHRIFT FUR EVIDENZ FORTBILDUNG UND QUALITAET IM GESUNDHEITSWESEN | 2010年 / 104卷 / 04期
关键词
meta-analysis; publication bias; small-study effects; funnel plot; Egger test; trim-and-fill method;
D O I
10.1016/j.zefq.2010.03.016
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Publication bias in meta-analysis occurs if the probability of publication depends on the estimated treatment effect and the precision / size of a study. In this article we describe the funnel plot as a graphical method to evaluate the presence of publication bias. Furthermore, tests of publication bias based on funnel plots are explained, and methods are presented that estimate treatment effects adjusted for publication bias. The article closes with a critical discussion of the various statistical methods.
引用
收藏
页码:306 / 313
页数:8
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