Serum YKL-40 Levels in Patients with Esophageal Squamous Cell Carcinoma

被引：1

作者：

Yilmaz, Ozkan ^{[1
]}

Kemik, Ozgur ^{[1
]}

Kemik, Ahu ^{[2
]}

Sumer, Aziz ^{[1
]}

Dulger, A. Cumhur ^{[3
]}

Asirci, Ismail ^{[1
]}

Almali, Nejat ^{[1
]}

Purisa, Sevim ^{[4
]}

Kotan, Cetin ^{[1
]}

机构：

[1] Yuzuncu Yil Univ, Med Fac, Dept Gen Surg, Van, Turkey

[2] Istanbul Univ, Cerrahpasa Med Fac, Dept Biochem, Istanbul, Turkey

[3] Yuzuncu Yil Univ, Med Fac, Dept Gastroenterol, Van, Turkey

[4] Istanbul Univ, Istanbul Med Fac, Dept Biostat, Istanbul, Turkey

来源：

CANCER GROWTH AND METASTASIS | 2011年 / 4卷

关键词：

esophageal squamous cell carcinoma; YKL-40;

D O I：

10.4137/CGM.S7046

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aims and background: YKL-40 is a glycoprotein secreted by macrophages, neutrophils and malignant tumor cells. YKL-40 is expressed and secreted by several types of tumors. The aim of this study examined the clinical usefulness of YKL-40 for detection in esophageal squamous cell carcinoma (ESCC). Methods: Using ELISA kits, we measured the concentration of YKL-40 in serum from 100 patients with ESCC and compared this concentration with healthy population. Results: We found significantly higher serum levels of YKL-40 in patients with ESCC compared to the healthy population (P < 0.0001). Conclusions: These results suggested that regarding serum YKL-40 as a tumor marker could be benefical in the early clinical diagnosis.

引用

页码：1 / 5

页数：5

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