CHIRAL LIGANDS CONTAINING HETEROATOMS .8. 2-[(2S)-2-PYRROLIDINYL]PYRIDINE AS A NOVEL CATALYST IN THE ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES

被引：81

作者：

CHELUCCI, G ^{[1
]}

CONTI, S ^{[1
]}

FALORNI, M ^{[1
]}

GIACOMELLI, G ^{[1
]}

机构：

[1] UNIV SASSARI,DIPARTMENTO CHIM,VIA VIENNA 2,I-07100 SASSARI,ITALY

来源：

TETRAHEDRON | 1991年 / 47卷 / 38期

关键词：

D O I：

10.1016/S0040-4020(01)91018-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound has been demonstrated to be an effective enantioselective catalyst in the addition of diethylzinc to aldehydes: optically active secondary alcohols in up to 100% ee were obtained in high yields. The temperature dependence of the stereodynamic course of the reaction was examined and the nature of the possible catalytic complex was discussed on the basis of NMR data too.

引用

页码：8251 / 8258

页数：8

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