Aggregation Of Thrombocytes In Patients With Arterial Hypertension And Impaired Glucose Tolerance

It has long been noted in modern society the growth in the number of patients suffering from both arterial hypertension and impaired glucose tolerance. For these patients, a high incidence of thrombosis is associated with hyperaggregation of their blood cells. The goal is to evaluate the aggregation capacity of platelets in patients with arterial hypertension with impaired glucose tolerance. We examined 49 patients of the second adulthood (mean age 52.4 +/- 1.9 years) with arterial hypertension 1-2 degrees, risk 4 with impaired glucose tolerance. The control group consisted of 26 clinically healthy people of the same age. All examined persons gave written informed consent to participate in the study. Biochemical, hematological and statistical methods of investigation were used in the work. The high incidence of thrombosis in various locations with hypertension with impaired glucose tolerance is apparently closely related to the development of platelet hyperaggregation. A serious cause of its occurrence in conditions of a combination of arterial hypertension with impaired glucose tolerance is the weakening of the antioxidant protection of the plasma with the activation of the processes of lipid peroxidation in it. It was found that people with arterial hypertension and impaired glucose tolerance have an obvious weakening of platelet disaggregation. As a result, patients receive a sharply increased risk of thrombosis of any location, which can lead to disability and death.