L-DOPA AND CEREBROSPINAL FLUID HOMOVANILLIC ACID IN PARKINSONISM

被引：55
作者：
WEINER, W
HARRISON, W
KLAWANS, H
机构：
[1] Department of Neurology, Presbyterian-St. Luke's Hospital, Chicago, IL 60612
来源：
LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 17P1期
关键词：
D O I：
10.1016/0024-3205(69)90428-7
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Lumbar cerebral spinal fluid of 19 patients with parkinsonism was analyzed for homovanillic acid before and during treatment with L-dopa. There was a marked rise in homovanillic acid concentration during treatment in all patients. This is the first indication that L-dopa results in increased utilizations of dopamine within the central nervous system. © 1969.
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页码：971 / &
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