INCORPORATION OF 6-THIOINOSINE INTO OLIGORIBONUCLEOTIDES

被引：7

作者：

ADAMS, CJ ^{[1
]}

FARROW, MA ^{[1
]}

MURRAY, JB ^{[1
]}

KELLY, SM ^{[1
]}

PRICE, NC ^{[1
]}

STOCKLEY, PG ^{[1
]}

机构：

[1] UNIV STIRLING,DEPT BIOL & MOLEC SCI,STIRLING FK9 4LA,SCOTLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 26期

关键词：

D O I：

10.1016/0040-4039(95)00805-M

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Preparation of S-6-cyanoethyl-6-thioinosine and its incorporation into oligoribonucleotides, using standard phosphoramidite methods, is described. Evidence for binding between the minimal RNA recognition sequence (minSLIIB) and the cognate HIV-1-GST-Rev protein was obtained from the changes in the unique circular dichroism band at 320 nm of 6-thioinosine.

引用

页码：4637 / 4640

页数：4

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