IS THE ACRAL-LENTIGINOUS MELANOMA (ALM) MORE MALIGNANT THAN THE SUPERFICIAL SPREADING MELANOMA (SSM) IN A HIGH-RISK LOCATION - A MATCHED-PAIR COMPARISON OF 113 EACH ALM AND SSM IN A MULTICENTER STUDY

被引：13

作者：

BREUNINGER, H

KOHLER, C

DREPPER, H

BASTIAN, B

BROCKER, EB

GOHL, J

GROTH, W

HERMANEK, P

HOHENBERGER, W

LIPPOLD, A

KOLMEL, K

LANDTHALER, M

PETERS, A

TILGEN, W

机构：

[1] FACHKLIN HORNHEIDE MUNSTER,MUNSTER,GERMANY

[2] UNIV WURZBURG,HAUT KLIN,W-8700 WURZBURG,GERMANY

[3] UNIV ERLANGEN NURNBERG,CHIRURG KLIN,W-8520 ERLANGEN,GERMANY

[4] UNIV COLOGNE,CHIRURG KLIN,W-5000 COLOGNE 41,GERMANY

[5] UNIV GOTTINGEN,CHIRURG KLIN,W-3400 GOTTINGEN,GERMANY

[6] UNIV REGENSBURG,DERMATOL KLIN,W-8400 REGENSBURG,GERMANY

[7] UNIV HEIDELBERG,CHIRURG KLIN,W-6900 HEIDELBERG,GERMANY

[8] GERMAN CANC RES CTR,W-6900 HEIDELBERG 1,GERMANY

来源：

HAUTARZT | 1994年 / 45卷 / 08期

关键词：

ACRAL-LENTIGINOUS MELANOMA; SUPERFICIAL SPREADING MELANOMA; PROGNOSIS; MATCHED PAIR STUDY;

D O I：

10.1007/s001050050120

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Even today, the prognosis of acrallentiginous melanoma (ALM) remains a controversial topic. We present a large case study including all known factors relevant for prognosis. 113 ALMs in 3616 melanoma patients were paired as precisely as possible with their twins, i.e. with 113 superficial spreading melanomas (SSM) from a group of 619 SSMs with high-risk location. The ALMs and SSMs were equivalent in tumor thickness, patient gender and mode of treatment. The follow-up period was for at least 5 years. The 5-year Kaplan-Meier survival curve in both groups are identical. The poor prognosis often ascribed to ALM results from the prognostic factor location. ALM should therefore be regarded as acral localized melanoma.

引用

页码：529 / 531

页数：3

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