QUALITY-OF-LIFE MEASURES FOR PATIENTS RECEIVING ADJUVANT THERAPY FOR BREAST-CANCER - AN INTERNATIONAL TRIAL

被引：69

作者：

HURNY, C ^{[1
]}

BERNHARD, J ^{[1
]}

GELBER, RD ^{[1
]}

COATES, A ^{[1
]}

CASTIGLIONE, M ^{[1
]}

ISLEY, M ^{[1
]}

DREHER, D ^{[1
]}

PETERSON, H ^{[1
]}

GOLDHIRSCH, A ^{[1
]}

SENN, HJ ^{[1
]}

机构：

[1] IBCSG OPERAT OFF,CH-3007 BERN,SWITZERLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1992年 / 28A卷 / 01期

关键词：

D O I：

10.1016/0959-8049(92)90399-M

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Serial quality of life (QL) assessments are being obtained every 3 months for 2 years from patients with operable breast cancer in two ongoing International Breast Cancer Study Group (IBCSG) randomised clinical trials of adjuvant treatment. The QL-assessments include patient-derived perceived coping (PACIS, personal adjustment to chronic illness scale), well-being (Bf-S, Befindlichkeitsskala von Zerssen), mood, physical well-being and appetite (LASA, linear analogue self assessments). The first assessment within 6 weeks of surgery was performed by 70% of the patients. The analysis of serial assessments for 265 patients with each of the first four assessments completed showed that all measures improved with increasing time from study entry; that the degrees of improvement for the four major language groups were similar; and that measures were sensitive to treatment difference. In conclusion, measurement of QL related aspects in a multicultural clinical trial is feasible and possibly relevant for the evaluation of treatment results.

引用

页码：118 / 124

页数：7

共 35 条

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