Facile synthesis, characterization and antimicrobial activities of diphenylphosphoryl derivatives of substituted aryl and nitrogen heterocycles

被引:0
作者
Reddy, G. Subba [1 ]
Rao, K. Uma Maheswara [1 ]
Sudha, S. Santhi [1 ]
Reddy, N. Bakthavatchala [1 ]
Sundar, Ch. Syama [1 ]
Raju, C. Naga [1 ]
Reddy, C. Suresh [1 ]
机构
[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India
关键词
Diphenylphosphoryl derivatives; nitrogen heterocycles; antibacterial activity; antifungal activity;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Diphenylphosphoryl derivatives of substituted aryl and nitrogen heterocycles were prepared by a one-pot process involving sequential reaction of diphenylphosphine chloride with dry methyl alcohol/ethyl alcohol and then with different halides of substituted nitrogen heterocycles/aryl halides. The title compounds (5a-j) structures were established by analytical, IR, NMR (H-1, C-13 and P-31) and mass spectra, and they have been screened for their antimicrobial activity. They exhibited significant antibacterial and antifungal activity.
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页码:41 / 46
页数:6
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