LOCALIZATION OF CD44 (P80) ON THE EXTERNAL SURFACE OF A HUMAN ASTROCYTOMA CELL

被引：20

作者：

GIRGRAH, N ^{[1
]}

ACKERLEY, CA ^{[1
]}

MOSCARELLO, MA ^{[1
]}

机构：

[1] HOSP SICK CHILDREN,RES INST,DEPT PATHOL,TORONTO M5G 1X8,ONTARIO,CANADA

来源：

NEUROREPORT | 1991年 / 2卷 / 08期

关键词：

CD44; ASTROCYTOMA; CELL ADHESION MOLECULE;

D O I：

10.1097/00001756-199108000-00007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A brain antigen, originally identified by a MAb 44D10, has been shown to be a glycoprotein with an Mr of 80 kDa. Cellular localization studies of sections of brain showed that the antigen was associated with the membrane of astrocytes. In the present study we demonstrate its localization to the membrane of an astrocytoma cell line by fluorescence and electron microscopic immunogold methods. Heavy labelling with immunogold was found along cellular processes. Labelling of the smooth surfaces of cells and the microvilli was also observed.

引用

页码：441 / 444

页数：4

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