INTERACTION OF ALGINATES AND PECTINS WITH CATIONIC POLYPEPTIDES

被引：44
作者：
BYSTRICKY, S
MALOVIKOVA, A
STICZAY, T
机构：
[1] Institute of Chemistry, Centre for Chemical Research, Slovak Academy of Sciences
来源：
CARBOHYDRATE POLYMERS | 1990年 / 13卷 / 03期
关键词：
Acids; -; Polypeptides; Interactions;
D O I：
10.1016/0144-8617(90)90060-6
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The interactions of alginates of various compositions and of pectins with basic polypeptides, namely, poly(l-lysine) and poly(Lys-Ala-Ala), have been studied by means of circular dichroism. The complexation efficiency of both types of anionic polysaccharides were compared and quantified on the basis of the extent of the induced α-helical conformation of the polypeptide. The alginate with a high content of guluronic acid (∼ 75%) did not interact with poly(l-lysine). Pectins and alginates interacted with poly(Lys-Ala-Ala) rather intensively. The difference in efficiency of interaction of l-guluronan and d-galacturonan with poly(l-lysine) results from the difference in the conformational flexibility of their polyanionic chains in solution. l-Guluronan maintains the rigid two-fold symmetry in solution, and d-galacturonan is conformationally adaptable in the course of interaction. © 1990.
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页码：283 / 294
页数：12
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