PRESENCE OF L-AMINO-ACID OXIDASE IN BLOOD IN PEMPHIGUS DERMATITIS HERPETIFORMIS DUHRING AND HERPES ZOSTER

被引：0
作者：
MECHER, T
MASSZI, J
机构：
[1] State Institute of Dermato- Venereology and University Clinic for Skin and Venereal Diseases Post address: VIII. Maria u 41. Budapest, Hungary.
来源：
CLINICA CHIMICA ACTA | 1969年 / 24卷 / 01期
关键词：
D O I：
10.1016/0009-8981(69)90147-8
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
In the sera of pemphigus, dermatitis herpetiformis Duhring and herpes zoster patients L-amino-acid oxidases are present. The enzyme in pemphigus serum is inhibited by 2,4-dinitrophenyl hvdrazine, iodoacetic acid, 8-hydroxyquinoline, hydroxylamine, sodium azide, octanol, p-chloro-mercuribenzoate, 2,4-dinitrophenol and p-aminobenzoate. The specificity of L-amino-acid oxidase present in pemphigus serum of an untreated patient is determined. The good significance values of the L-glutamic acid oxidations permit the clinical laboratory control of the effectivity of glucocorticoid treatment in pemphigus. The biochemical mechanism and the possible physiological significance of the enzyme activity are discussed. © 1968.
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页码：111 / &
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