DIASTEREOSELECTIVITY IN THE HYDROXYL-DIRECTED CYCLOPROPANATION OF VINYLORGANOMETALLIC COMPOUNDS

被引：41

作者：

LAUTENS, M

DELANGHE, PHM

机构：

[1] Department of Chemistry, University of Toronto, Toronto, Ontario

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 03期

关键词：

D O I：

10.1021/jo00029a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Olefins bearing silicon and/or tin substituents undergo highly diastereoselective cyclopropanation in the presence of Sm/CH2I2. The stereochemistry of the tin moiety has a dramatic effect on the rate of a subsequent transmetalation with MeLi.

引用

页码：798 / 800

页数：3

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