STUDIES ON MECHANISM OF ACTION OF GOUGEROTIN .2. EFFECT OF VARIOUS FACTORS ON GOUGEROTIN ACTION

被引：5

作者：

YUKIOKA, M

MORISAWA, S

机构：

[1] Department of Biochemistry, Osaka City University Medical School, Abeno-ku, Osaka

来源：

JOURNAL OF BIOCHEMISTRY | 1969年 / 66卷 / 02期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a129139

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of gougerotin was examined on the essential components necessary for the poly U directed polyphenylalanine synthesis in the E. coli cell free system. The reaction was carried out under a condition where one of the components is a rate-limiting step of the overall polyphenylalanine formation. Of the essential components, T factor and poly U affected the gougerotin action. The increment of their amounts did decrease the inhibition of polyphenylalanine synthesis by gougerotin at low salt concentrations, and enhanced the gougerotin-dependent-stimulation of polyphenylalanine formation at higher salt concentrations.The possible explanation for these findings was discussed. © 1969 BY THE JOURNAL OF BIOCHEMISTRY.

引用

页码：233 / &

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