4-YEAR FOLLOW-UP OF 24 1ST-EPISODE MANIC PATIENTS

被引：130
作者：
TOHEN, M
WATERNAUX, CM
TSUANG, MT
HUNT, AT
机构：
[1] MCLEAN HOSP,PSYCHOSIS PROGRAM,BELMONT,MA 02178
[2] HARVARD UNIV,SCH MED,DEPT PSYCHIAT,HARVARD PROGRAM PSYCHIAT EPIDEM,BOSTON,MA 02115
[3] BROCKTON W ROXBURY VET ADM CTR,PSYCHIAT SERV,BROCKTON,MA
[4] HARVARD UNIV,SCH MED,DEPT EPIDEMIOL,HARVARD PROGRAM PSYCHIAT EPIDEMIOL,BOSTON,MA 02115
[5] HARVARD UNIV,SCH PUBL HLTH,DEPT BIOSTAT,BOSTON,MA 02115
来源：
JOURNAL OF AFFECTIVE DISORDERS | 1990年 / 19卷 / 02期
关键词：
First episode; Mania; Outcome; Survival analysis;
D O I：
10.1016/0165-0327(90)90012-W
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Twenty-four first-episode manic patients were followed to investigate the 4-year outcome after recovery from a manic episode. Patients had no documented previous manic or depressive episodes. The presence of psychotic features during the index episode and a history of alcoholism were statistically significant predictors of a shorter time in remission. Low occupational status at baseline predicted poor global social adjustment at 4 years. Also, a larger correlation among outcome measures was found at 48 than at 6 months. The importance of controlling for presence of multiple episodes in outcome studies is emphasized. © 1990.
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页码：79 / 86
页数：8
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