ENDOGENOUS PROSTAGLANDINS IN PEPTIC-ULCER DISEASE

被引：37
作者：
BAKER, R [1 ]
JAFFE, BM [1 ]
VENABLES, CW [1 ]
机构：
[1] WASHINGTON UNIV,SCH MED,ST LOUIS,MO 63130
来源：
GUT | 1979年 / 20卷 / 05期
关键词：
D O I：
10.1136/gut.20.5.394
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Plasma concentrations of prostaglandins E and F have been measured by radioimmunoassay in patients undergoing diagnostic upper intestinal endoscopy. The results fail to support a previously reported deficiency of plasma PGE in duodenal ulcer patients. Plasma prostaglandin concentrations failed to correlate with the parameters of gastric secretion studied; and were unaffected by histamine H2-receptor blockade or the activity of duodenal ulceration. During combined pentagastrin and insulin secretory studies there was a significant correlation between the outputs of PGE and acid into gastric juice.
引用
收藏
页码：394 / 399
页数：6
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