DIFFERENTIAL-EFFECTS OF BASOLATERAL AMYGDALA LESIONS ON BEHAVIOR, CORTICOSTERONE, AND PROLACTIN RESPONSES

被引:9
|
作者
SEGGIE, J
机构
[1] Jo Seggie, Ph.D., is an Ontario Mental Health Foundation Research Associate
[2] Dr. Seggie is also Associate Professor, Departments of Neurosciences and Psychiatry, McMaster University
关键词
Amygdala; behavior; corticosterone; prolactin; stress;
D O I
10.1016/0165-1781(79)90010-6
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The present experiment examines hormone-behavior relationships following manipulation of the amygdala. Affective behavior and levels of corticosterone and prolactin were compared in rats with lesions of the basolateral amygdala and in nonlesioned and sham-operated controls. Animals with lesions of the basolateral amygdala were found to be hyperreactive and to have normal resting levels of corticosterone and prolactin but potentiated corticosterone responses to stress. Normal prolactin stress responses were unaltered by the lesion. The results are discussed in relation to behavioral and endocrine changes seen following other limbic system lesions. © 1979.
引用
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页码:283 / 295
页数:13
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