DRUG-METABOLISM BY HUMAN CYTOCHROME P4502D6 - STUDIES OF THE ENZYME CLONED IN YEAST

被引:0
|
作者
CHING, MS
ELLIS, SW
GHABRIAL, HG
LENNARD, MS
TUCKER, GT
SMALLWOOD, RA
机构
[1] UNIV MELBOURNE,HEIDELBERG REPATRIAT HOSP,DEPT MED,PARKVILLE,VIC 3052,AUSTRALIA
[2] UNIV SHEFFIELD,ROYAL HALLAMSHIRE HOSP,DEPT MED & PHARMACOL,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:A888 / A888
页数:1
相关论文
共 50 条
  • [21] A patient with treatment-resistant schizophrenia and cytochrome P4502D6 gene duplication
    Kawanishi, C
    Furuno, T
    Kishida, I
    Matsumura, T
    Kosaka, K
    CLINICAL GENETICS, 2002, 61 (02) : 152 - 154
  • [22] Inhibition of cytochrome P4502D6 (CYP2D6) by terbinafine (TER) in vitro.
    Abdel-Rahman, SM
    Marcucci, K
    Boge, T
    Gotschall, RR
    Kearns, GL
    Leeder, JS
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1999, 65 (02) : 135 - 135
  • [23] Effect of nonspecific binding to microsomes and metabolic elimination of buprenorphine on the inhibition of cytochrome P4502D6
    Umeda, S
    Harakawa, N
    Yamamoto, M
    Ueno, K
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (02) : 212 - 216
  • [24] Influence of the cytochrome P4502D6*4 allele on the pharmacokinetics of controlled-release metoprolol
    R. Koytchev
    R.-G. Alken
    V. Vlahov
    V. Kirkov
    R. Kaneva
    U. Thyroff-Friesinger
    E. Rehak
    European Journal of Clinical Pharmacology, 1998, 54 : 469 - 474
  • [25] A sensitive method for determination of cytochrome P4502D6 activity in vitro using bupranolol as substrate
    Appanna, G
    Tang, BK
    Muller, R
    Kalow, W
    DRUG METABOLISM AND DISPOSITION, 1996, 24 (03) : 303 - 306
  • [26] Influence of the cytochrome P4502D6*4 allele on the pharmacokinetics of controlled-release metoprolol
    Koytchev, R
    Alken, RG
    Vlahov, V
    Kirkov, V
    Kaneva, R
    Thyroff-Friesinger, U
    Rehak, E
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1998, 54 (06) : 469 - 474
  • [27] Propranolol hydroxylation and N-desisopropylation by cytochrome P4502D6 - Studies using the yeast-expressed enzyme and NADPH/O-2 and cumene hydroperoxide-supported reactions
    Bichara, N
    Ching, MS
    Blake, CL
    Ghabrial, H
    Smallwood, RA
    DRUG METABOLISM AND DISPOSITION, 1996, 24 (01) : 112 - 118
  • [28] 细胞色素P4502D6与药物代谢
    王娜
    刘会臣
    侯艳宁
    中国临床药理学杂志, 2001, (04) : 308 - 312
  • [29] A novel enzyme linked immunosorbent assay for the detection of antibodies to cytochrome P4502D6, the molecular target of liver kidney microsomal antibody
    Kerkar, N
    Hussain, M
    Targett, C
    MieliVergani, G
    Vergani, D
    HEPATOLOGY, 1997, 26 (04) : 1641 - 1641
  • [30] P4502D6 genotypes in inflammatory bowel disease (IBD).
    Crotty, B
    Tikelis, C
    GASTROENTEROLOGY, 1996, 110 (04) : A889 - A889