TRANSMISSION OF VARICELLA-ZOSTER VIRUS FROM A VACCINEE WITH LEUKEMIA, DEMONSTRATED BY POLYMERASE CHAIN-REACTION

被引：24
作者：
HUGHES, P
LARUSSA, P
PEARCE, JM
LEPOW, M
STEINBERG, S
GERSHON, A
机构：
[1] COLUMBIA UNIV, COLL PHYS & SURG, DEPT PEDIAT, NEW YORK, NY 10032 USA
[2] ALBANY MED COLL, ALBANY, NY USA
来源：
JOURNAL OF PEDIATRICS | 1994年 / 124卷 / 06期
关键词：
D O I：
10.1016/S0022-3476(05)83185-3
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
A 5-year-old white boy in remission from ac ute lymphoblastic leukemia who was receiving maintenance anticancer chemotherapy had approximately 200 vesicular skin lesions 1 month after receiving live attenuated varicella vaccine. About 2 to 3 weeks later, a mild illness resembling varicella occurred in his susceptible siblings and in three of his classmates. Vaccine-type varicella-zoster virus was demonstrated by polymerase chain reaction in swab specimens from vesicular lesions in his two siblings, in whom antibody to varicella-zoster virus also developed.
引用
收藏
页码：932 / 935
页数：4
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