Clinical Characteristics of False-Positive Lymph Node on Chest CT or PET-CT Confirmed by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Lung Cancer

被引：22

作者：

Lee, Jongmin ^{[1
]}

Kim, Young Kyoon ^{[1
]}

Seo, Ye Young ^{[2
]}

Choi, Eun Kyoung ^{[3
]}

Lee, Dong Soo ^{[4
]}

Kim, Yeon Sil ^{[4
]}

Hong, Sook Hee ^{[5
,6
]}

Kang, Jin Hyoung ^{[5
,6
]}

Lee, Kyo Young ^{[7
]}

Park, Jae Kil ^{[8
]}

Sung, Sook Whan ^{[8
]}

Kim, Hyun Bin ^{[9
,10
]}

Park, Mi Sun ^{[9
,10
]}

Yim, Hyeon Woo ^{[9
,10
]}

Kim, Seung Joon ^{[1
,6
]}

机构：

[1] Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Div Pulm,Dept Internal Med, Seoul, South Korea

[2] Inje Univ, Sanggye Paik Hosp, Dept Nucl Med, Seoul, South Korea

[3] Catholic Univ Korea, Coll Med, Dept Radiol, Seoul, South Korea

[4] Catholic Univ Korea, Coll Med, Dept Radiat Oncol, Seoul, South Korea

[5] Catholic Univ Korea, Coll Med, Div Med Oncol, Seoul, South Korea

[6] Catholic Univ Korea, Coll Med, Canc Res Inst, Seoul, South Korea

[7] Catholic Univ Korea, Coll Med, Dept Hosp Pathol, Seoul, South Korea

[8] Catholic Univ Korea, Coll Med, Dept Thorac Surg, Seoul, South Korea

[9] Catholic Univ Korea, Coll Med, Dept Biostat, Seoul, South Korea

[10] Catholic Univ Korea, Coll Med, Clin Res Coordinating Ctr, Seoul, South Korea

来源：

TUBERCULOSIS AND RESPIRATORY DISEASES | 2018年 / 81卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

Lymph Node; Chest; Tomography; X-Ray Computed; Positron Emission Tomography Computed Tomography; Lung Neoplasms;

D O I：

10.4046/trd.2017.0121

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a standard procedure to evaluate suspicious lymph node involvement of lung cancer because computed tomography (CT) and 18 F-fluorodeoxyglucose positron emission tomography-CT (PET-CT) have limitations in their sensitivity and specificity. There are a number of benign causes of false positive lymph node such as anthracosis or anthracofibrosis, pneumoconiosis, old or active tuberculosis, interstitial lung disease, and other infectious conditions including pneumonia. The purpose of this study was to evaluate possible causes of false positive lymph node detected in chest CT or PET-CT. Methods: Two hundred forty-seven patients who were initially diagnosed with lung cancer between May 2009 and December 2012, and underwent EBUS-TBNA to confirm suspicious lymph node involvement by chest CT or PET-CT were analyzed for the study. Results: Of 247 cases, EBUS-TBNA confirmed malignancy in at least one lymph node in 189. The remaining 58 patients whose EBUS-TBNA results were negative were analyzed. Age >= 65, squamous cell carcinoma as the histologic type, and pneumoconiosis were related with false-positive lymph node involvement on imaging studies such as chest CT and PET-CT. Conclusion: These findings suggest that lung cancer staging should be done more carefully when a patient has clinically benign lymph node characteristics including older age, squamous cell carcinoma, and benign lung conditions.

引用

页码：339 / 346

页数：8

共 24 条

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