Scientific Opinion on the substantiation of health claims related to soy protein and contribution to the maintenance or achievement of a normal body weight (ID 598), maintenance of normal blood cholesterol concentrations (ID 556) and protection of DNA, proteins and lipids from oxidative damage (ID 435) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

被引：2

作者：

Agostoni, Carlo ^{[1
]}

Bresson, Jean-Louis ^{[1
]}

Fairweather-Tait, Susan ^{[1
]}

Flynn, Albert ^{[1
]}

Golly, Ines ^{[1
]}

Korhonen, Harmu ^{[1
]}

Lagiou, Pagona ^{[1
]}

Lovik, Martinus ^{[1
]}

Marchelli, Rosangela ^{[1
]}

Martin, Ambroise ^{[1
]}

Moseley, Bevan ^{[1
]}

Neuhaeuser-Berthold, Monika ^{[1
]}

Przyrembel, Hildegard ^{[1
]}

Salminen, Seppo ^{[1
]}

Sanz, Yolanda ^{[1
]}

Strain, Sean ^{[1
]}

Strobel, Stephan ^{[1
]}

Tetens, Inge ^{[1
]}

Tome, Daniel ^{[1
]}

van Loveren, Hendrik ^{[1
]}

Verhagen, Hans ^{[1
]}

机构：

[1] EFSA, Parma, Italy

来源：

EFSA JOURNAL | 2010年 / 8卷 / 10期

关键词：

Soy protein; body weight; blood cholesterol; oxidative damage; health claims;

D O I：

10.2903/j.efsa.2010.1812

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health claims in relation to soy protein and contribution to the maintenance or achievement of a normal body weight, maintenance of normal blood cholesterol concentrations and protection of DNA, proteins and lipids from oxidative damage. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituent that is the subject of the health claims is soy protein. The Panel considers that soy protein is sufficiently characterised. Contribution to the maintenance or achievement of a normal body weight The claimed effect is "weight control". The target population is assumed to be the general population. The Panel considers that contribution to the maintenance or achievement of a normal body weight is a beneficial physiological effect. In weighing the evidence, the Panel took into account that the only study that allowed conclusions to be drawn for the scientific substantiation of the claim showed no effect of soy protein on body weight when compared to other protein sources. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of soy protein and contribution to the maintenance or achievement of a normal body weight. Maintenance of normal blood cholesterol concentrations The claimed effect is "control of cholesterol". The target population is assumed to be the general population. In the context of the proposed wording and clarifications provided by Member States, the Panel assumes that the claimed effect refers to the maintenance of normal blood cholesterol concentrations. A claim on soy protein and the reduction of blood cholesterol concentrations has already been assessed with an unfavourable outcome. All of the references provided in the consolidated list, and which addressed the effects of soy protein on blood cholesterol concentrations, were considered in this previous Opinion. Protection of DNA, proteins and lipids from oxidative damage The claimed effect is "antioxidant health". The target population is assumed to be individuals performing physical exercise. In the context of the proposed wording, the Panel assumes that the claimed effect refers to the protection of DNA, proteins and lipids from oxidative damage caused by free radicals that are generated during physical exercise. The Panel considers that the protection of DNA, proteins and lipids from oxidative damage may be a beneficial physiological effect. The Panel considers that no conclusions could be drawn from the two human studies provided for the scientific substantiation of the claimed effect because they do not allow one to distinguish between the effects of the protein component of soy (which is the subject of the health claim) and those of soy isoflavones on lipid peroxidation. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of soy protein and the protection of DNA, proteins and lipids from oxidative damage.

引用

页数：17

共 10 条

[1] A novel soy-based meal replacement formula for weight loss among obese individuals: a randomized controlled clinical trial [J].