INHIBITION OF INSULIN AND SOMATOSTATIN SECRETION AND STIMULATION OF GLUCAGON-RELEASE BY HOMOLOGOUS GALANIN IN PERFUSED RAT PANCREAS

被引：26
作者：
MIRALLES, P [1 ]
PEIRO, E [1 ]
DEGANO, P [1 ]
SILVESTRE, RA [1 ]
MARCO, J [1 ]
机构：
[1] UNIV AUTONOMA MADRID,HOSP PUERTA HIERRO,SERV ENDOCRINOL EXPTL,SAN MARTIN PORRES 4,E-28035 MADRID,SPAIN
来源：
DIABETES | 1990年 / 39卷 / 08期
关键词：
D O I：
10.2337/diabetes.39.8.996
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：996 / 1001
页数：6
相关论文
共 35 条
[1]   GALANIN INHIBITS GLUCOSE-STIMULATED INSULIN RELEASE BY A MECHANISM INVOLVING HYPERPOLARIZATION AND LOWERING OF CYTOPLASMIC FREE CA-2+ CONCENTRATION [J].
AHREN, B ;
ARKHAMMAR, P ;
BERGGREN, PO ;
NILSSON, T .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (03) :1059-1063
[2]   GALANIN RECEPTORS IN A HAMSTER PANCREATIC BETA-CELL TUMOR - IDENTIFICATION AND MOLECULAR CHARACTERIZATION [J].
AMIRANOFF, B ;
SERVIN, AL ;
ROUYERFESSARD, C ;
COUVINEAU, A ;
TATEMOTO, K ;
LABURTHE, M .
ENDOCRINOLOGY, 1987, 121 (01) :284-289
[3]   MECHANISM OF GALANIN-INHIBITED INSULIN RELEASE - OCCURRENCE OF A PERTUSSIS-TOXIN-SENSITIVE INHIBITION OF ADENYLATE-CYCLASE [J].
AMIRANOFF, B ;
LORINET, AM ;
LAGNYPOURMIR, I ;
LABURTHE, M .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 177 (01) :147-152
[4]   STRUCTURAL REQUIREMENT FOR GALANIN ACTION IN THE PANCREATIC BETA-CELL LINE RIN M-5F [J].
AMIRANOFF, B ;
LORINET, AM ;
YANAIHARA, N ;
LABURTHE, M .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1989, 163 (01) :205-207
[5]  
BAUER FE, 1986, LANCET, V2, P192
[6]   GALANIN - A NOVEL PANCREATIC NEUROPEPTIDE [J].
DUNNING, BE ;
AHREN, B ;
VEITH, RC ;
BOTTCHER, G ;
SUNDLER, F ;
TABORSKY, GJ .
AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 251 (01) :E127-E133
[7]   GALANIN RELEASE DURING PANCREATIC NERVE-STIMULATION IS SUFFICIENT TO INFLUENCE ISLET FUNCTION [J].
DUNNING, BE ;
TABORSKY, GJ .
AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 256 (01) :E191-E198
[8]  
Faloona G.R, 1974, METHOD HORM RADIOIMM, P317
[9]   HIGH-DOSE PORCINE GALANIN INFUSION AND EFFECT ON INTRAVENOUS GLUCOSE-TOLERANCE IN HUMANS [J].
GILBEY, SG ;
STEPHENSON, J ;
OHALLORAN, DJ ;
BURRIN, JM ;
BLOOM, SR .
DIABETES, 1989, 38 (09) :1114-1116
[10]   MEASUREMENTS OF SOMATOSTATIN-LIKE IMMUNOREACTIVITY IN PLASMA [J].
HARRIS, V ;
CONLON, JM ;
SRIKANT, CB ;
MCCORKLE, K ;
SCHUSDZIARRA, V ;
IPP, E ;
UNGER, RH .
CLINICA CHIMICA ACTA, 1978, 87 (02) :275-283
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