CROSS SECTIONAL ANALYSIS ON RELATIONSHIP BETWEEN RISK FACTORS DIABETES AND DR: RESEARCH HELD IN LAHORE

被引:0
作者
Zubair, Muhammad [1 ]
Shafique, Aisha [2 ]
Aezaz, Ayesha [1 ]
机构
[1] BVH, Bahawalpur, Pakistan
[2] Medicare Hosp Multan, Multan, Pakistan
来源
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2018年 / 5卷 / 11期
关键词
HbA1c (AASH & KMDC 18(2):86; 2013); Insulin Dependent Diabetes Mellitus (IDDM); Non-Insulin Dependent; Diabetes Mellitus (NIDDM); Diabetes mellitus; Diabetic Retinopathy (DR);
D O I
10.5281/zenodo.1477657
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Aim: The purpose of this research was to evaluate the relation of Diabetic Retinopathy (DR) with Diabetes Mellitus (DM) by examining the glycemic control, mode used for curing, type and duration of DM. Study Type: Cross ectional analysis.Time and Place: Completed the study in the time duration of 06 months started from January,2018 and ended in June, 2018 at Mayo, Hospital Lahore. Methodology and material: Made the selection of total 108 patients by using non-probability, convenient sampling method. Only selected those patients, either found victims of non-insulin dependent diabetes mellitus (NIDDM) or insulin dependent diabetes mellitus (IDDM) also called Type-II and Type-I diabetes. Carried of complete analyses of every patient and collected all previous antiquity information by them. Through glycosylated hemoglobin level (HbAIc) carried out the assessment of Glycaemic-control. Used a pre-designed proforma for the collection of whole data. Performed the analysis of all information by the help of SPSS software V.16. Results: Found Type-I (IDDM) & Type-II (NIDDM) diabetes, after the examination as 30.6% (33) and 69.4% (75) respectively out of total 108 diabetes patients. There were 49.3% (37) women and 54.5% (18) ladies in Type-II and Type-1 groups accordingly. Observed DR in a few patients as < 5 years time period in these two groups which was 15.69% in Type-II and 12.59% in Type-I. Comparison of Type-I & Type-II groups showed that there was DR in 60.61% (20) and 37.29% (28) patients respectively with P-value as less than 0.005. With the time period of more 20 years of diabetes, the Diabetic Retinopathy (DR) raised as 77.69% in Type-II patients with P-value less than 0.02 and 100% in Type-I diabetes patients with P-value as less than 0.001.Found Diabetic Retinopathy (DR)as 53.09% in Type-II cases with oral hypoglycaemics and/or diet therapy and 60.59% in Type-I sufferers who were under the treatment of insulin therapy. Found no sign of Diabetic Retinopathy (DR)in any patient of either group who was with HbA1c <7%.Conclusion: Found direct connection of greater level of HbA1c with the growth of Diabetic Retinopathy (DR). Patients of Type-I diabetes who were under the treatment of insulin therapy for a long period of time were having higher occurrence of Diabetic Retinopathy (DR) than the patients of Type-II diabetes patients
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页码:11400 / 11405
页数:6
相关论文
共 29 条
[1]   BLOOD-GLUCOSE CONCENTRATIONS AND PROGRESSION OF DIABETIC-RETINOPATHY - THE 7 YEAR RESULTS OF THE OSLO STUDY [J].
BRINCHMANNHANSEN, O ;
DAHLJORGENSEN, K ;
SANDVIK, L ;
HANSSEN, KF .
BRITISH MEDICAL JOURNAL, 1992, 304 (6818) :19-22
[2]   CONTROL AND DIABETES [J].
CAHILL, GF ;
ETZWILER, DD ;
FREINKEL, N .
NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (18) :1004-1005
[3]   Benefits of Ophdiat®, a telemedical network to screen for diabetic retinopathy: A retrospective study in five reference hospital centres [J].
Chabouis, A. ;
Berdugo, M. ;
Meas, T. ;
Erginay, A. ;
Laloi-Michelin, M. ;
Jouis, V. ;
Guillausseau, P. -J. ;
M'Bemba, J. ;
Chaine, G. ;
Slama, G. ;
Cohen, R. ;
Reach, G. ;
Marre, M. ;
Chanson, P. ;
Vicaut, E. ;
Massin, P. .
DIABETES & METABOLISM, 2009, 35 (03) :228-232
[4]   The relationship between socioeconomic status and diabetes control and complications in the EURODIAB IDDM complications study [J].
Chaturvedi, N ;
Stephenson, JM ;
Fuller, JH .
DIABETES CARE, 1996, 19 (05) :423-430
[5]  
Chaudhry GM, 2005, PAK J MED RES, V44, P82
[6]   AUTOMATED DIAGNOSIS OF RETINOPATHY BY CONTENT-BASED IMAGE RETRIEVAL [J].
Chaum, Edward ;
Karnowski, Thomas P. ;
Govindasamy, V. Priya ;
Abdelrahman, Mohamed ;
Tobin, Kenneth W. .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2008, 28 (10) :1463-1477
[7]   Burden of illness of diabetic macular edema: literature review [J].
Chen, Er ;
Looman, Mark ;
Laouri, Marianne ;
Gallagher, Meghan ;
Van Nuys, Karen ;
Lakdawalla, Darius ;
Fortuny, Joan .
CURRENT MEDICAL RESEARCH AND OPINION, 2010, 26 (07) :1587-1597
[8]   Association of A1C and Fasting Plasma Glucose Levels With Diabetic Retinopathy Prevalence in the US Population Implications for diabetes diagnostic thresholds [J].
Cheng, Yiling J. ;
Gregg, Edward W. ;
Geiss, Linda S. ;
Imperatore, Giuseppina ;
Williams, Desmond E. ;
Zhang, Xinzhi ;
Albright, Ann L. ;
Cowie, Catherine C. ;
Klein, Ronald ;
Saaddine, Jinan B. .
DIABETES CARE, 2009, 32 (11) :2027-2032
[9]   Diabetic retinopathy [J].
Cheung, Ning ;
Mitchell, Paul ;
Wong, Tien Yin .
LANCET, 2010, 376 (9735) :124-136
[10]   Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes. [J].
Chew, Emily Y. ;
Ambrosius, Walter T. ;
Davis, Matthew D. ;
Danis, Ronald P. ;
Gangaputra, Sapna ;
Greven, Craig M. ;
Hubbard, Larry ;
Esser, Barbara A. ;
Lovato, James F. ;
Perdue, Letitia H. ;
Goff, David C., Jr. ;
Cushman, William C. ;
Ginsberg, Henry N. ;
Elam, Marshall B. ;
Genuth, Saul ;
Gerstein, Hertzel C. ;
Schubart, Ulrich ;
Fine, Lawrence J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (03) :233-244