THE FERTILITY POTENTIAL OF MALE CYSTIC-FIBROSIS PATIENTS

被引：18

作者：

GOTTLIEB, C

PLOEN, L

KVIST, U

STRANDVIK, B

机构：

[1] KAROLINSKA HOSP,DEPT CLIN CHEM,ANDROL UNIT,S-10401 STOCKHOLM 60,SWEDEN

[2] SWEDISH UNIV AGR SCI,FAC VET MED,DEPT ANAT & HISTOL,S-75007 UPPSALA,SWEDEN

[3] HUDDINGE HOSP,DEPT PEDIAT,S-14186 HUDDINGE,SWEDEN

来源：

INTERNATIONAL JOURNAL OF ANDROLOGY | 1991年 / 14卷 / 06期

关键词：

D O I：

10.1111/j.1365-2605.1991.tb01272.x

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

Men suffering from cystic fibrosis (CF) are considered to be infertile because of azoospermia. In testicular biopsies from two patients with CF normal spermatogenesis was found despite the absence of sperm in the ejaculate. Fructose and prostaglandin were not detectable in the semen whereas the levels of acid phosphatase and zinc were within normal limits, indicating normal prostatic function and absence of seminal vesicles. These findings may improve the possibility for male patients with CF to father a child.

引用

页码：437 / 440

页数：4

共 17 条

[1] HYPOTHESIS REVISITED - CYSTIC-FIBROSIS - A DISTURBANCE OF WATER AND ELECTROLYTE MOVEMENT IN EXOCRINE SECRETORY TISSUE ASSOCIATED WITH ALTERED PROSTAGLANDIN (PGE2) METABOLISM [J].

ANDERSON, CM .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1984, 3 (01) :15-22

[2]

BENDVOLD E, 1986, J REPROD FERTIL, V78, P311

[3] 15-KETO-13,14-DIHYDROPROSTAGLANDIN-E2-METABOLITE AND F2-ALPHA METABOLITE LEVELS IN BLOOD FROM MEN AND WOMEN GIVEN PROSTAGLANDIN-E2 ORALLY [J].

BREMME, K ;

ENEROTH, P ;

GOTTLIEB, C ;

KINDAHL, H ;

SVANBORG, K ;

NILSSON, B ;

OLSSON, M ;

BYGDEMAN, M .

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 1989, 37 (03) :169-176

[4]

DENNING CR, 1968, PEDIATRICS, V41, P7

[5]

GRANSTROM E, 1982, METHOD ENZYMOL, V86, P320

[6]

HODSON M, 1986, CYSTIC FIBROSIS

[7] GENITAL ABNORMALITIES IN MALE PATIENTS WITH CYSTIC FIBROSIS [J].

HOLSCLAW, DS ;

PERLMUTTER, AD ;

JOCKIN, H ;

SHWACHMAN, H .

JOURNAL OF UROLOGY, 1971, 106 (04) :568-+

[8]

HOLSTEIN AF, 1983, FORTSCHRITTE ANDROLO, V8, P108

[9] REPRODUCTION FAILURE IN MALES WITH CYSTIC FIBROSIS [J].

KAPLAN, E ;

SHWACHMA.H ;

PERLMUTT.AD ;

RULE, A ;

KHAW, KT ;

HOLSCLAW, DS .

NEW ENGLAND JOURNAL OF MEDICINE, 1968, 279 (02) :65-&

[10]

LANDING BH, 1969, ARCH PATHOL, V88, P569

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