RAPID QUANTITATIVE-DETERMINATION OF BLOOD-ALCOHOL CONCENTRATION IN THE EMERGENCY DEPARTMENT USING AN ELECTROCHEMICAL METHOD

被引：3

作者：

WAX, PM

HOFFMAN, RS

GOLDFRANK, LR

机构：

[1] Department of Emergency Medicine, Bellevue Hospital Center, New York University School of Medicine

[2] The New York City Poison Control Center, New York City

来源：

ANNALS OF EMERGENCY MEDICINE | 1992年 / 21卷 / 03期

关键词：

BLOOD ALCOHOL CONCENTRATION; TESTING;

D O I：

10.1016/S0196-0644(05)80884-4

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Study objective: To determine the reliability of a recently developed electrochemical meter to rapidly (within 60 seconds) measure blood alcohol concentration (BAC) in the emergency department. Design: A prospective study comparing the meter data with that of immunoassay and gas chromatography criterion standards undertaken during a ten-week period. Setting: Adult ED of a municipal hospital. Participants: Three hundred eighty-three consecutive patients with altered mental status or suspected alcohol intoxication. Interventions: Each patient underwent routine phlebotomy, and blood samples were obtained for meter and immunoassay BAC determinations. The first 60% of patients also underwent gas chromatography BAC determination. Results: Two hundred nineteen patients (60%) had BAC detectable by both meter and immunoassay. BAC measurement by the meter correlated strongly with immunoassay and gas chromatography determinations (Pearson's correlation coefficient, r = .94; P < .00000001 for both correlations). Conclusion: The electrochemical meter provides a rapid and reliable BAC measurement in the ED.

引用

页码：254 / 259

页数：6

共 19 条

[1]

Walsh, Macleod, Breath alcohol analysis in the accident and emergency department, Injury, 15, pp. 62-66, (1983)

[2]

Gibb, Serum alcohol levels, toxicology screens, and use of the breath alcohol analyzer, Ann Emerg Med, 15, pp. 349-353, (1986)

[3]

Jatlow, Acute toxicology of ethanol ingestion: Role of the clinical laboratory, Am J Clin Pathol, 74, pp. 721-724, (1980)

[4]

Lester, Breath tests for alcohol, N Engl J Med, 284, pp. 1269-1270, (1971)

[5]

Gibb, Yee, Johnston, Et al., Accuracy and usefulness of a breath alcohol analyzer, Ann Emerg Med, 13, pp. 516-520, (1984)

[6]

Alobaidi, Hill, Payne, Significance of variations in blood:breath partition coefficient of alcohol, Br Med J, 2, pp. 1479-1481, (1976)

[7]

Kaye, The collection and handling of the blood alcohol specimen, Am J Clin Pathol, 74, pp. 743-746, (1980)

[8]

Spector, Alcohol breath tests Gross errors in current methods of measuring alveolar gas concentrations, Science, 173, pp. 57-59, (1971)

[9]

Buchwald, Smith, Saliva teststrips for alcohol testing, Ann Emerg Med, 19, pp. 342-343, (1990)

[10]

Rodenberg, Bennett, Watson, Clinical utility of a saliva alcohol dipstick estimate of serum ethanol concentrations in the emergency department, DICP Ann Pharmacotherap, 24, pp. 358-361, (1990)

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