NORMAL AND PATHOLOGICAL GROWTH OF ARTERIAL SMOOTH-MUSCLE

被引：0
作者：
CAPRON, L [1 ]
机构：
[1] HOP BROUSSAIS, SERVE MED INTERNE & PATHOL VASC, F-75674 PARIS 14, FRANCE
来源：
ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX | 1991年 / 84卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In addition to contractility, arterial smooth muscle cells, like all connective tissue cells, have a capacity to proliferate and synthesize extracellular matrix. Under different normal (development, aging) and abnormal circumstances (high blood pressure, atherosclerosis, balloon angioplasty), smooth muscle cells express these properties which characterize the dedifferentiated phenotype. This paper reviews the main mechanisms, modulations and possible therapeutic implications of dedifferentiation.
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页码：15 / 24
页数：10
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