Hemoglobin Content and Total Red Blood Cell Count in Different Ethnic Groups of Assam with a Special Reference to Glucose 6 Phosphate Dehydrogenase

Introduction: Although glucose-6-phosphate dehydrogenase (G6PD) deficient individuals are generally asymptomatic throughout their life, the clinical burden of this genetic condition includes a range of hematological conditions, including acute hemolytic anemia, neonatal jaundice, and chronic non-spherocytic anemia. Materials and Methods: Samples were collected randomly from 80 people (18-45 yrs) of different ethnic groups in Jorhat District. Hemoglobin estimation was done by cyanmethemoglobin method. Total red blood cell (RBC) count was done by using hemocytometer. Quantitative estimation of G6PD is done by kit method. Results: Correlation coefficient between G6PD status and hemoglobin was 0.072. This correlation was found to be statistically insignificant (P > 0.05), and a negative correlation was noted to establish a relationship between the above two parameters. Correlation coefficient between G6PD status and RBC count was -0.21. This correlation was found to be statistically insignificant (P > 0.05), and a negative correlation was noted to establish a relationship between the above two parameters. Conclusion: From this study, it can be concluded that a negative correlation exists between G6PD status and hemoglobin content and RBC count.