VASOACTIVE PEPTIDES AND UTERINE VESSELS

被引：6
作者：
STJERNQUIST, M [1 ]
BODELSSON, G [1 ]
POULSEN, H [1 ]
机构：
[1] LUND UNIV,DEPT OBSTET & GYNECOL MALMO,MALMO,SWEDEN
来源：
GYNECOLOGICAL ENDOCRINOLOGY | 1995年 / 9卷 / 02期
关键词：
VASOACTIVE PEPTIDES; UTERINE ARTERY; UMBILICAL ARTERY; ENDOTHELIN; ATRIAL NATRIURETIC PEPTIDE; ANGIOTENSIN; PREECLAMPSIA;
D O I：
10.3109/09513599509160207
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Endothelins and atrial natriuretic peptide (ANP) are vasoactive peptides with effects on the human uterine and umbilical arteries. Endothelin (ET) contracts the vascular smooth muscle. Both ET(A)- and non-ET(A)-non-ET(B)-receptors seem to be involved. Autoradiography reveals binding of ET to vascular smooth muscle. ANP counter-acts the contractile effects of angiotensin II in the human uterine artery. Head-down tilt results in elevation of plasma ANP in healthy pregnant women, while the same manoeuvre induces down-regulation of the renin-angiotensin-aldosterone system in non-pregnant women and patients suffering from pre-eclampsia.
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收藏
页码：165 / 176
页数：12
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共 78 条
[1]  
Furchgott R.F., Zawadzki J.V., The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine, Nature (London), 288, pp. 373-376, (1980)
[2]  
Furchgott R.F., Role of endothelium in responses of vascular smooth muscle, Circ. Res, 35, pp. 557-573, (1983)
[3]  
Palmer R.M.J., Ferrige A.G., Moncada S., Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor, Nature (London), 327, pp. 524-526, (1987)
[4]  
Moncada S., Gryglewski R., Bunting S., Vane J.R., An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable sustance that inhibits platelet aggregation, Nature (London), 263, pp. 663-665, (1976)
[5]  
Feletou M., Vanhoutte P.M., Endothelium-derived factor(s) and membrane potential of vascular smooth muscle, Blood Vessels, 23, (1986)
[6]  
Zawaditsky J.V., Furchgott R.F., Cherry P., The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by substance P (abstr.), Fed. Proc, 40, (1981)
[7]  
Cherry P.D., Furchgott R.F., Zawaditsky J.V., The indirect nature of bradykinin relaxation of isolated arteries: endothelial dependent and independent components (abstr.), Fed. Proc, 40, (1981)
[8]  
van de Voorde J., Leusen I., Role of endothelium in the vasodilator response of thoracic aorta to histamine, Eur. J. Pharmacol, 87, pp. 113-120, (1983)
[9]  
Edvinsson L., Fredholm B., Hamel E., Jansen I., Verrecchia C., Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat, Neurosci. Lett, 58, pp. 213-217, (1985)
[10]  
Bodelsson G., Stjernquist M., Smooth muscle dilatation in human uterine artery induced by substance P, vasoactive intestinal polypeptide, calcitonin gene-related peptide and atrial natriuretic peptide: relation to endothelium-derived relaxing substances, Hum. Reprod, 7, pp. 1185-1188, (1992)
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