PRESYNAPTIC EXCITABILITY CHANGES INDUCED BY MORPHINE IN SINGLE CUTANEOUS AFFERENT C-FIBERS AND A-FIBERS

被引：83
作者：
CARSTENS, E [1 ]
TULLOCH, I [1 ]
ZIEGLGANSBERGER, W [1 ]
ZIMMERMANN, M [1 ]
机构：
[1] MAX PLANCK INST PSYCHIAT,D-8000 MUNICH 40,FED REP GER
来源：
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 1979年 / 379卷 / 02期
关键词：
C-fiber terminals; Excitability testing; Morphine; Presynaptic inhibition;
D O I：
10.1007/BF00586940
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Intraspinal microstimulation was used to test the excitability of single cutaneous (sural) A- and C-fibers at their central terminals in the cat. Systemic morphine (1.0-2.6 mg/kg) increased the antidromic threshold to 110% (mean value) of control in C-fibers. In some of the C-fibers this effect was reversed by naloxone. A-fibers were not consistently affected by mophine. © 1979 Springer-Verlag.
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页码：143 / 147
页数：5
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