MULTIPLE-SCLEROSIS - AN AUTOIMMUNE-DISEASE OF MULTIFACTORIAL ETIOLOGY

被引：82
作者：
BERNARD, CCA
DEROSBO, NK
机构：
[1] La Trobe University, Buncloora, Vic.
来源：
CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 06期
关键词：
D O I：
10.1016/0952-7915(92)90058-M
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The etiology of multiple sclerosis is linked to a variety of genetic and environmental factors. Both cell-mediated and humoral immune responses, triggered by extraneous or autoantigens, are likely to contribute to the pathogenesis of this disease. A greater insight into the fundamental cause of multiple sclerosis has been provided by the recognition that certain immune response genes are associated with an increased susceptibility to the disease. Such knowledge should provide new opportunities for selective therapeutic interventions.
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页码：760 / 765
页数：6
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