EFFICACY OF 2 TRIMETHOPRIM-SULFONAMIDE COMBINATIONS IN EXPERIMENTAL PYELONEPHRITIS IN THE RAT

被引：0

作者：

RITZERFELD, W

机构：

[1] Hygiene-Institut der Universität Münster, Münster

来源：

INFECTION | 1979年 / 7卷

关键词：

D O I：

10.1007/BF01639010

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Co-trimazine, a new combination of trimethoprim and sulphadiazine intended for treatment of urinary tract infections, was and compared to co-trimoxazole in an experimental model of acute, obstructive pyelonephritis in the rat. The tests were carried out at four dose levels corresponding to the clinically recommended doses and to 1/4, 1/2, and 3/4 of the latter. The drugs were administered orally. Co-trimazine was found to have a greater antibacterial activity than co-trimoxazole and its use at a lower dosage than that of the latter appears warranted. © 1979 Verlagsgesellschaft Otto Spatz.

引用

页码：S342 / S344

页数：3