STUDIES ON CURCUMIN AND CURCUMINOIDS .23. EFFECTS OF CURCUMIN ON LIPOSOMAL LIPID-PEROXIDATION

被引：0
|
作者：
TONNESEN, HH [1 ]
SMISTAD, G [1 ]
AGREN, T [1 ]
KARLSEN, J [1 ]
机构：
[1] UNIV OSLO,BIOTECHNOL CTR OSLO,N-0316 OSLO 3,NORWAY
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 90卷 / 03期
关键词：
CURCUMIN; RADICAL SCAVENGER; PHOTOSENSITIZER; CHELATING AGENT; LIPOSOMAL LIPID PEROXIDATION;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The potential of curcumin as a photosensitzer, radical scavenger and iron-chelating agent within an artificial membrane (i.e., liposome) is discussed. Curcumin is found to have a dual effect on liposome stability, manifested as peroxidation of phospholipids in the membrane. Curcumin incorporated in the liposomes acts as a chelating agent of ferric and ferrous ions in the membrane.
引用
收藏
页码：221 / 228
页数：8
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