RESULTS OF CLASSICAL IVF IN MALE-INFERTILITY

Between 1988 and 1993, FIVNAT register collected data on 1 218 IVF cycles, with less than 500 000 motile and morphologically normal ejaculated spermatozoa per mi on the day of IVF. 700 embryo transfers were performed (57,5 % per oocyte retrieval) and the mean number of transferred embryos was 2,4 +/- 1,0. 175 clinical pregnancies were obtained : consequently the clinical pregnancy rate was 14,4 % per puncture and 25,0 % per transfer: The pregnancy outcome is knowned for 102 clinical pregnancies (58,3 %) and is similar to that of clinical pregnancies obtained from normal sperm. When sperm characteristics dysplay such alterations, numeration lower than 5 millions per mi and total motility lower than 10 % impair cleavage rate. The effect of teratozoospermia is not clear, because in this study severe teratozoospermia (> 90 %) were associated with high numeration and motility.