UNSUCCESSFUL DIETARY-TREATMENT OF SJOGREN-LARSSON SYNDROME

被引：19

作者：

MAASWINKELMOOIJ, PD

BROUWER, OF

RIZZO, WB

机构：

[1] LEIDEN UNIV HOSP, DEPT NEUROL, 2333 AA LEIDEN, NETHERLANDS

[2] VIRGINIA COMMONWEALTH UNIV MED COLL VIRGINIA, DEPT PEDIAT, RICHMOND, VA USA

[3] VIRGINIA COMMONWEALTH UNIV MED COLL VIRGINIA, DEPT HUMAN GENET, RICHMOND, VA USA

来源：

JOURNAL OF PEDIATRICS | 1994年 / 124卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(05)81369-1

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We treated five children with Sjogren-Larsson syndrome. The patients, 5 months to 8 years of age, were given a low fat diet supplemented with medium-chain fatty acids. Plasma octadecanol levels remained unchanged, and skin lesions and neurologic symptoms did not abate. Two patients also failed to respond to dietary supplementation with polyunsaturated fatty acids. We conclude that dietary therapy is usually unsuccessful in patients with Sjogren-Larsson syndrome even when started in early infancy.

引用

页码：748 / 750

页数：3

共 7 条

[1] SJOGREN-LARSSON SYNDROME - REPORT OF 2 CASES IN TWINS [J].