THE ROLE OF LIPID-PEROXIDATION AND CALCIUM IN GALACTOSAMINE INDUCED TOXICITY IN THE RAT-LIVER

被引：0
|
作者：
SECKIN, S [1 ]
KOCAKTOKER, N [1 ]
UYSAL, M [1 ]
OZ, B [1 ]
机构：
[1] ISTANBUL UNIV, CERRAHPASA FAC MED, DEPT PATHOL, ISTANBUL, TURKEY
来源：
RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY | 1993年 / 80卷 / 01期
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D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Liver homogenate and subcellular fractional levels of lipid peroxides, homogenate glutathione (GSH) and calcium contents and hepatic plasma membrane Ca2+-ATPase activity were determined in rats 12,18,24 and 48 hours after treatment with a single dose of 1 g/kg galactosamine. Lipid peroxides and calcium levels in liver homogenate and subcellular fractions were found to increase, but hepatic GSH content and Ca2+-ATPase activity were observed to decrease reversibly.
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页码：117 / 120
页数：4
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