Current Trends in Preclinical PET System Design

被引：59

作者：

Levin, Craig S. ^{[1
]}

Zaidi, Habib ^{[2
]}

机构：

[1] Stanford Univ, Dept Radiol, Sch Med, Mol Imaging Program,Div Nucl Med, 300 Pasteur Dr,MC 5128,Alway Bldg,Room M001, Stanford, CA 94305 USA

[2] Geneva Univ Hosp, Div Nucl Med, CH-1211 Geneva, Switzerland

来源：

PET CLINICS | 2007年 / 2卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.cpet.2007.12.001

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

PET is used in laboratory small-animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease, and neurologic disorders in living small-animal models of disease. The current and next generation of PET molecular imaging probes, assays, and imaging systems still have substantial room to improve PET's ability to detect, visualize, and quantify low concentrations of probe interacting with its target, which we refer to as the molecular sensitivity. This article focuses on the challenges of advancing PET system and some of the new imaging system technologies under investigation to enhance PET's molecular sensitivity substantially.

引用

页码：125 / 160

页数：36

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