CALCIUM INTAKE, PHYSICAL-ACTIVITY AND BONE MASS IN PREMENOPAUSAL WOMEN

被引：14
作者：
NELSON, M
MAYER, AB
RUTHERFORD, O
JONES, D
机构：
[1] Department of Nutrition and Dietetics, King's College London, London, W8 7AH, Carnpden Hill Road
[2] Department of Medicine, University College of Middlesex School of Medicine, the Rayne Institute, London, WClE 6JJ, University Street
来源：
JOURNAL OF HUMAN NUTRITION AND DIETETICS | 1991年 / 4卷 / 03期
关键词：
CALCIUM INTAKE; PHYSICAL ACTIVITY; BONE MASS; PREMENOPAUSAL WOMEN; BREAST-FEEDING;
D O I：
10.1111/j.1365-277X.1991.tb00095.x
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Thirty pre-menopausal women aged 35-40 years were assessed with respect to dietary calcium intake, physical activity and other factors related to bone loss (by questionnaire); bone mass in the mid and distal femur measured by computerized tomography; and leg strength and muscle size. Cortical thickness at mid-femur was negatively associated with breast-feeding (r = -0.40). Bone mass in the distal femur was negatively associated with age (r = -0.46) and positively associated with activity (r = 0.44) and leg strength (r = 0.42). There was no association of bone mass at either site with current dietary calcium intake (range 198-1511 mg/day), nor with body mass index (BMI), hand-grip strength, parity, oral contraceptive use, smoking, or alcohol intake. Thus, in older pre-menopausal women, activity apparently helps to maintain bone mass at the distal femur, a site of high trabecular bone content, while current dietary-calcium intake has no effect on bone mass in the femur. Activity was most strongly associated with bone mass in the distal femur when it was defined as the total number of hours spent standing or moving (i.e. other than sitting or lying down), regardless of the intensity of activity. The strong negative association between bone mass in the distal femur and age in older pre-menopausal women is of concern in relation to long-term risk of osteoporotic related fracture, suggesting that factors relating to bone loss in this age-group should be studied longitudinally. The apparent loss of cortical bone in breast-feeders warrants further investigation.
引用
收藏
页码：171 / 177
页数：7
相关论文
共 32 条
  • [11] Infant feeding practices in Great Britain, (1988)
  • [12] Edwards R.H.T., Young A., Hosking G.P., Jones D.A., Human skeletal muscle function: description of tests and normal values, Clin. Sci. Mol. Med., 52, pp. 283-290, (1977)
  • [13] Emiola L., O'Shea J.P., Effects of physical activity and nutrition on bone density measured by radiographic techniques, Nutr. Rep. Inti., 17, pp. 669-681, (1978)
  • [14] Freudenheim J.L., Johnson M.S., Smith E.L., Relationships between usual nutrient intake and bone‐mineral content of women 35–65 years of age: longitudinal and cross‐sectional analysis, Am. J. Clin. Nutr., 44, pp. 863-876, (1986)
  • [15] Grindrod S.R., Tofts P., Edwards R.H.T., Investigation of human skeletal muscle structure and composition by X‐ray computerised tomography, Eur. J. Clin. Invest., 13, pp. 465-468, (1983)
  • [16] Halioua L., Anderson J.J.B., Lifetime calcium intake and physical activity habits: independent and combined effects on the radial bone of healthy pre‐monopausal Caucasian women, Am. J. Clin. Nutr., 49, pp. 534-541, (1989)
  • [17] Heaney R.P., Recker R.R., Saville P.D., Calcium balance and calcium requirements in middle‐aged women, Am. J. Clin. Nutr., 30, pp. 1603-1611, (1977)
  • [18] Heaney R.P., Gallagher J.C., Johnston C.C., Neer R., Parfitt A.M., Whedon G.D., Calcium nutrition and bone health in the elderly, Am. J. Clin. Nutr., 36, pp. 986-1013, (1982)
  • [19] Kanders B., Dempster D.W., Lindsay R., Interaction of calcium nutrition and physical activity on bone mass in young women, J. Bone Mineral Res., 3, pp. 145-149, (1988)
  • [20] Kriska A.M., Sandler R.B., Cauley J.A., La-Porte R.E., Horn D.L., Pambianco G., The assessment of historical physical activity and its relation to adult bone parameters, Am. J. Epidemiol., 1277, pp. 1053-1063, (1988)
1234