HISTOLOGICAL-CHANGES IN HAMSTER LIVER BY ES ANTIGEN OF ASCARIS-SUUM

被引：0

作者：

SANTRA, A ^{[1
]}

DUTTA, G ^{[1
]}

GHOSE, A ^{[1
]}

MAZUMDER, DNG ^{[1
]}

机构：

[1] INST POST GRAD MED EDUC & RES, DEPT GASTROENTEROL, CALCUTTA, INDIA

来源：

INDIAN JOURNAL OF MEDICAL RESEARCH SECTION A-INFECTIOUS DISEASES | 1993年 / 97卷

关键词：

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Polyacrylamide gel electrophoresis with SDS (PAGE-SDS) of the ES antigens of A. suum revealed several protein molecules which differed from those obtained in ES antigens of A. lumbricoides. Nature of liver damage caused by ES antigens of A. suum was studied in hamsters to find out the nature of damage and to compare with those caused by ES antigens of A. lumbricoides. Feeding of ES antigens of A. suum was carried out in 7 hamsters for 75 days. After such feeding gross hepatic damage was noticed. This was characterized by pericentrivenular degeneration and necrosis of liver parenchyma, the lesions being different and much more severe than those observed in hamster challenged by ES products of A. lumbricoides. The lesions appear to be immune mediated.

引用

页码：209 / 211

页数：3

共 9 条

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