TOTAL SYNTHESIS OF 2'-DEOXYCADEGUOMYCIN, A NEW PYRROLO[2,3-D]PYRIMIDINE NUCLEOTIDE ANALOG

被引：7

作者：

EDSTROM, ED

WEI, Y

机构：

[1] Department of Chemistry and Biochemistry, Utah State University Logan

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 48期

关键词：

D O I：

10.1016/0040-4039(94)88407-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes an efficient synthetic route to a novel pyrrolo[2,3-d]pyrimidine nucleotide analogue, 2'-deoxycadeguomycin 4a. The key transformation involves the conversion of the differentially protected pyrrolo[2,3-d]pyrimidin-2,4-dione base portion in la into a protected 2-amino-pyrrolo[2,3-d]pyrimidin-4-one 3a.

引用

页码：8989 / 8990

页数：2