SYNTHESIS OF 4-ARYL-3,5-BIS(ALKOXYCARBONYL)-1,4-DIHYDROPYRAZINES

被引：83

作者：

CHORVAT, RJ ^{[1
]}

RORIG, KJ ^{[1
]}

机构：

[1] GD SEARLE & CO,DEPT MED CHEM,SKOKIE,IL 60077

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1988年 / 53卷 / 24期

关键词：

D O I：

10.1021/jo00259a033

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：5779 / 5781

页数：3

共 11 条

[1] NIFEDIPINE THERAPY FOR CORONARY-ARTERY SPASM - EXPERIENCE IN 127 PATIENTS [J].

ANTMAN, E ;

MULLER, J ;

GOLDBERG, S ;

MACALPIN, R ;

RUBENFIRE, M ;

TABATZNIK, B ;

LIANG, CS ;

HEUPLER, F ;

ACHUFF, S ;

REICHEK, N ;

GELTMAN, E ;

KERIN, NZ ;

NEFF, RK ;

BRAUNWALD, E .

NEW ENGLAND JOURNAL OF MEDICINE, 1980, 302 (23) :1269-1273

[2] DIETHYL 3,6-DIHYDRO-2,4-DIMETHYL-2,6-METHANO-1,3-BENZOTHIAZOCINE-5,11-DICARBOXYLATES AS CALCIUM ENTRY ANTAGONISTS - NEW CONFORMATIONALLY RESTRAINED ANALOGS OF HANTZSCH 1,4-DIHYDROPYRIDINES RELATED TO NITRENDIPINE AS PROBES FOR RECEPTOR-SITE CONFORMATIONE [J].

BALDWIN, JJ ;

CLAREMON, DA ;

LUMMA, PK ;

MCCLURE, DE ;

ROSENTHAL, SA ;

WINQUIST, RJ ;

FAISON, EP ;

KACZOROWSKI, GJ ;

TRUMBLE, MJ ;

SMITH, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (04) :690-695

[3]

DIMROTH K, 1961, J LIEBIGS ANN CHEM, V639, P102

[4] SPECIFIC PHARMACOLOGY OF CALCIUM IN MYOCARDIUM, CARDIAC-PACEMAKERS, AND VASCULAR SMOOTH-MUSCLE [J].

FLECKENSTEIN, A .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1977, 17 :149-166

[5] CRYSTAL-STRUCTURES AND PHARMACOLOGICAL ACTIVITY OF CALCIUM-CHANNEL ANTAGONISTS - 2,6-DIMETHYL-3,5-DICARBOMETHOXY-4-(UNSUBSTITUTED, 3-METHYL-PHENYL, 4-METHYL-PHENYL, 3-NITRO-PHENYL, 4-NITRO-PHENYL, AND 2,4-DINITROPHENYL)-1,4-DIHYDROPYRIDINE [J].

FOSSHEIM, R ;

SVARTENG, K ;

MOSTAD, A ;

ROMMING, C ;

SHEFTER, E ;

TRIGGLE, DJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (02) :126-131

[6]

GUAZZI M, 1977, CLIN PHARMACOL THER, V22, P528

[7] NIFEDIPINE TABLETS FOR SYSTEMIC HYPERTENSION - A STUDY USING CONTINUOUS AMBULATORY INTRAARTERIAL RECORDING [J].

HORNUNG, RS ;

GOULD, BA ;

JONES, RI ;

SONECHA, TN ;

RAFTERY, EB .

AMERICAN JOURNAL OF CARDIOLOGY, 1983, 51 (08) :1323-1327

[8]

KONDO S, 1980, CHEM PHARM BULL, V28, P1

[9]

ROSENBERGER L, 1978, CALCIUM DRUG ACTION

[10] A STEREOCONTROLLED SYNTHESIS OF (+)-THIENAMYCIN [J].

SALZMANN, TN ;

RATCLIFFE, RW ;

CHRISTENSEN, BG ;

BOUFFARD, FA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (19) :6161-6163

← 1 2 →