EFFECTS OF LONG-TERM ZEARALENONE ADMINISTRATION ON SPERMATOGENESIS AND SERUM LUTEINIZING-HORMONE, FOLLICLE-STIMULATING-HORMONE, AND PROLACTIN VALUES IN MALE-RATS
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作者:
MILANO, GD
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机构:UNIV CTR PROV BUENOS AIRES,FAC CIENCIAS VET,DEPT FISIOPATOL,RA-7000 TANDIL,ARGENTINA
MILANO, GD
BECUVILLALOBOS, D
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机构:UNIV CTR PROV BUENOS AIRES,FAC CIENCIAS VET,DEPT FISIOPATOL,RA-7000 TANDIL,ARGENTINA
BECUVILLALOBOS, D
TAPIA, MO
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机构:UNIV CTR PROV BUENOS AIRES,FAC CIENCIAS VET,DEPT FISIOPATOL,RA-7000 TANDIL,ARGENTINA
TAPIA, MO
机构:
[1] UNIV CTR PROV BUENOS AIRES,FAC CIENCIAS VET,DEPT FISIOPATOL,RA-7000 TANDIL,ARGENTINA
[2] CONSEJO NACL INVEST CIENT & TECN,INST BIOL & MED EXPTL,RA-1428 BUENOS AIRES,DF,ARGENTINA
Body and testis weights, serum luteinizing hormone, follicle-stimulating hormone, and prolactin values and volume fractions of Sertoli cells, spermatogonia, early and late primary spermatocytes, and round and long spermatids were evaluated in 70-day-old male rats treated orally with 20 mg of zearalenone/kg of body weight daily for 5 weeks. A significant (P < 0.05) increase in serum prolactin concentration was consistently observed during the 5 weeks of treatment with zearalenone. Significant changes were not observed in any of the other variables evaluated.