AN INFLAMMATORY ERUPTION ASSOCIATED WITH RECOMBINANT HUMAN IL-6

被引：10
作者：
FLEMING, TE
MIRANDO, WS
SOOHOO, LF
COOPER, BW
ZAIM, MT
LAZARUS, HM
ELMETS, CA
机构：
[1] UNIV CLEVELAND HOSP,DEPT DERMATOL,CLEVELAND,OH 44106
[2] UNIV CLEVELAND HOSP,DEPT MED,CLEVELAND,OH 44106
[3] CASE WESTERN RESERVE UNIV,DEPT DERMATOL,CLEVELAND,OH 44106
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1994年 / 130卷 / 04期
关键词：
D O I：
10.1111/j.1365-2133.1994.tb03393.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Interleukin 6 (IL-6) is an endogenous cytokine with multiple biological functions, including amplification of the inflammatory response. Recombinant human IL-6, administered as part of a chemotherapeutic regimen, has recently been shown to cause regression of certain types of malignant tumours. We report a patient who developed a cutaneous eruption consisting of coalescent, erythematous, scaling macules and papules after administration of recombinant human IL-6, given as part of her chemotherapy for ductal carcinoma of the breast.
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收藏
页码：534 / 536
页数：3
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